Latest Research Developments

08/24/10: Health Benefits from Tea: Perception vs. Reality

WellGen’s own Dr. Shiming Li presented research about the analytical method for measuring polyphenols and the polyphenol content in ready-to-drink tea beverages at the American Chemical Society (ACS) meeting that began August 22 [...]

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Scientific Advisory Board

Dr. Chi‐Tang Ho

Professor, Dept. Food Science, Rutgers University: Natural products chemistry, Medicinal plants

Professor Chi-Tang Ho received his B.S. degree in chemistry from National Taiwan University in Taipei, Taiwan in 1968. He then went on to receive both his M.A. in 1971 and his Ph.D. in 1974 in organic chemistry from Washington University in St. Louis. After completing two years as a postdoctorate fellow at Rutgers University, he joined the faculty at Rutgers University as an assistant professor in the Department of Food Science. He was promoted to associate professor in 1983. In 1987 he was promoted to Professor I, and in 1993 he was promoted to Professor II. Dr. Ho has published over 360 papers and scientific articles, and is an editorial board member for a variety of publications, including the Journal of Agricultural and Food Chemistry. He has also won numerous awards including two honorary professorships, and has served in the Division of Agricultural and Food Chemistry of the American Chemical Society in various positions including as division chair.

Dr. Dan Notterman

Professor, Princeton University and NJ Cancer Institute, Director of Transcriptional Profiling Core: Gene‐environment interactions, gene expression analysis, bioinformatics

Dr. Daniel Notterman received a B.A. from Cornell University, an M.A. in Philosophy from Tufts University, and his M.D. from New York University School of Medicine, where he completed his internship and residency. He is also Founder and Director of the Transcriptional Profiling Core Facility at the NJ Cancer Center, UMDNJ. Dr. Notterman has been a research fellow in clinical pharmacology at Cornell and in molecular biology at Princeton. He is the former director of the Pediatric Intensive Care Unit at Bellevue Hospital Center and the former director of the Division of Pediatric Critical Care Medicine.

Dr. Derek LeRoith

Chair, Dept. Endocrinology, Mt. Sinai Medical Center; former President, ADA; former Chair, Diabetes Section NIH‐NIDDK: Metabolism, Diabetes
PROFESSOR  Medicine, Endocrinology, Diabetes and Bone Disease 
SubspecialtyEndocrinology, Diabetes and Metabolism

Dr. Derek LeRoith’s education and training include: MD, University of Cape Town Med School Ph.D., University of Cape Town Senior Resident, The Middlesex Hospital Residency, Internal Medicine, University of Cape Town Internship, Internal Medicine, University of Cape Town.

Prior to joining the faculty of Mount Sinai School of Medicine in 2005 as Professor of Medicine and Chief of the Division of Endocrinology, Diabetes and Bone Disease, Dr. LeRoith was Chief of the Diabetes Branch at the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases. This is the largest program devoted to the study of diabetes within the intramural program of the NIH. He has published over 500 original research papers, reviews and editorials and edited a number of books on Diabetes and IGF-related topics. He is also the senior editor of a major textbook on Diabetes, now in its third edition.

Clinical support for WellGen® theaflavin- rich black tea concentrate:

Human Clinical Study 1:

Systemic Inflammation Study LPS (lipopolysaccharide)- mediated challenge exposes the inflammation cascade and is a fundamental pharmaceutical inflammation probe.

Key findings

  • Reduces expression of pro-inflammatory mRNA and cytokines/chemokines proteins
  • Inflammatory biomarker levels ranging between two-to-four fold less than the placebo group
  • Elevation of immuno-modulatory cytokine IL-10

Human Clinical Study 2:

Exercise-induced Inflammation - Test the effects in high-intensity anaerobic exercise on:

  • Delayed onset muscle soreness (DOMS)
  • Oxidative stress
  • Cortisol response
  • Inflammatory biomarkers

Key findings

  • Reduces damage and inflammation due to exercise related stress
  • Promotes rapid post-exercise recovery
  • Improves capacity to exercise
  • Reduces oxidative stress markers
  • Relieves delayed onset muscle soreness due

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